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Anti-Inflammatory High Purity CAS 36322-90-4 Medicial Piroxicam Powder

Basic Information
Place of Origin: Shaanxi, China
Brand Name: bio
Certification: GMP, ISO, SGS, QS, HALAL, HPLC
Model Number: Piroxicam
Minimum Order Quantity: 1kg
Price: /
Packaging Details: 1-25kg bag, 25kg drum
Delivery Time: 1-3 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500 kgs per month
Detail Information
Product Name: Piroxicam Cas No.: 36322-90-4
EINECS No.: 252-974-3 Assay: Purity 99%
Usage: Anti-Inflammatory Storage: Cool Dry Place
COA: Available Brand: Bio

Product Description

Anti-Inflammatory CAS 36322-90-4 Medicial Piroxicam Powder

Meloxicam Introduction:

Product Name:Piroxicam 
Chemical Name:
4 - Hydroxy - 2 - methyl - N - (2 - pyridinyl) - 2H - pyridine - 3 - carboxamide
CAS No: 36322-90-4
Molecular weight: 331.35

 

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the oxicam group. It is renowned for its analgesic, anti-inflammatory, and antipyretic effects and is widely used in clinical practice. Piroxicam exerts its therapeutic effects by inhibiting the enzyme cyclooxygenase (COX), which is responsible for synthesizing prostaglandins—key substances that mediate inflammation, pain, and fever.

 

Chemical Structure and Properties

Piroxicam has the chemical name 4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-pyridine-3-carboxamide. Its molecular formula is C₁₅H₁₃N₃O₃, with a molecular weight of approximately 275.28 g/mol. It appears as a white to off-white crystalline powder, slightly soluble in water but more soluble in organic solvents such as ethanol

 

Mechanism of Action

Piroxicam works by inhibiting cyclooxygenase (COX), thereby reducing the synthesis of prostaglandins. There are two main isoforms of COX: COX-1 and COX-2. COX-1 is primarily involved in normal physiological functions, such as protecting the gastric mucosa and regulating platelet aggregation, while COX-2 is induced during inflammation and is responsible for producing inflammatory prostaglandins. Although Piroxicam inhibits both COX-1 and COX-2, its selectivity for COX-2 is lower compared to some other NSAIDs (such as Meloxicam). By reducing prostaglandin synthesis, Piroxicam effectively alleviates pain, reduces inflammation, and lowers fever.

 

Clinical Uses
Piroxicam is used to treat a variety of inflammatory and painful conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, and mild to moderate pain (such as postoperative pain, dental pain, and dysmenorrhea).

 

Key Actions of Piroxicam

 

1.Analgesic (Pain Relief)
Reduces mild to moderate pain, including postoperative, dental, and menstrual pain.
2.Anti-inflammatory (Reduces Inflammation)
Alleviates swelling and inflammation in conditions like rheumatoid arthritis, osteoarthritis, and gout.
3.Antipyretic (Reduces Fever)
Helps lower fever by acting on the hypothalamus.
4.Long-Acting
Long half-life (20-50 hours) allows for once-daily dosing, providing sustained relief.
5.Chronic Condition Management
Effective for long-term management of chronic inflammatory diseases like ankylosing spondylitis and osteoarthritis.
Piroxicam Specification:
Product name Piroxicam
CAS 36322-90-4
EINECS 200-270-1
MF C17H20N2O2S
MW 331.346
Melting point 198-200°C
Appearance Powder

 

Anti-Inflammatory High Purity CAS 36322-90-4 Medicial Piroxicam Powder 0

 

 

 

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