|Place of Origin:||Shaanxi, China|
|Certification:||GMP, ISO, SGS, QS, HALAL, HPLC|
|Minimum Order Quantity:||25kg|
|Price:||$47-$57 per kilogram|
|Packaging Details:||1-25kg bag, 25kg drum|
|Delivery Time:||1-3 work days|
|Payment Terms:||T/T, Western Union, MoneyGram|
|Supply Ability:||5300 kg per month|
|Product Name:||Levofloxacin||EINECS No.:||600-146-0|
|Cas No.:||100986-85-4||Appearance:||White Fine Powder|
|Molecular Formula:||C18H20FN3O4||Molecular Weight:||361.37|
|Grade:||Pharmaceutical Grade||Place Of Origin:||Shaanxi, China|
bactericidal and bacteriostatic antibiotics,
uti antibiotic cephalexin
Top quality API Levofloxacin antibiotic powder CAS.100986-85-4 with best price
Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic. The Levofloxacin powder is used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, and some types of gastroenteritis. Along with other antibiotics it may be used to treat tuberculosis, meningitis, or pelvic inflammatory disease. The levofloxacin powder is available by mouth, intravenously,and in eye drop form.
Common side effects include nausea, diarrhea, and trouble sleeping. Serious side effects may include tendon rupture, tendon inflammation, seizures, psychosis, and potentially permanent peripheral nerve damage. Tendon damage may appear months after treatment is completed. People may also sunburn more easily. In people with myasthenia gravis, muscle weakness and breathing problems may worsen. The risk of use during pregnancy is low and it is probably okay during breastfeeding. Levofloxacin is a broad-spectrum antibiotic of the fluoroquinolone drug class. It usually results in death of the bacteria. It is the left sided isomer of the medication ofloxacin.
1. Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, endocarditis, meningitis, pelvic inflammatory disease, traveler's diarrhea, tuberculosis, and plague and is available by mouth, intravenously,and in eye drop form.
As of 2016, the US Food and Drug Administration (FDA) recommended that "serious side effects associated with fluoroquinolone antibacterial drugs generally outweigh the benefits for patients with acute sinusitis, acute bronchitis, and uncomplicated urinary tract infections who have other treatment options. For patients with these conditions, fluoroquinolones should be reserved for those who do not have alternative treatment options."
2. Levofloxacin is used for the treatment of pneumonia, urinary tract infections, and abdominal infections. As of 2007 the Infectious Disease Society of America (IDSA) and the American Thoracic Society recommended levofloxacin and other respiratory fluoroquinolines as first line treatment for community acquired pneumonia when co-morbidities such as heart, lung, or liver disease are present or when in-patient treatment is required. Levofloxacin also plays an important role in recommended treatment regimens for ventilator-associated and healthcare-associated pneumonia.
As of 2010 it was recommended by the IDSA as a first-line treatment option for catheter-associated urinary tract infections in adults.In combination with metronidazole it is recommended as one of several first-line treatment options for adult patients with community-acquired intra-abdominal infections of mild-to-moderate severity. The IDSA also recommends it in combination with rifampicin as a first-line treatment for prosthetic joint infections. The American Urological Association recommends levofloxacin as a first-line treatment to prevent bacterial prostatitis when the prostate is biopsied.and as of 2004 levofloxacin powder was recommended to treat bacterial prostatitis by the NIH research network studying the condition.
Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Like all quinolones, it functions by inhibiting the two type II topoisomerase enzymes, namely DNA gyrase and topoisomerase IV. Topoisomerase IV is necessary to separate DNA that has been replicated (doubled) prior to bacterial cell division. With the DNA not being separated, the process is stopped, and the bacterium cannot divide. DNA gyrase, on the other hand, is responsible for supercoiling the DNA, so that it will fit in the newly formed cells. Both mechanisms amount to killing the bacterium. In this way, levofloxacin acts as a bactericide.
|Storage||Keep away from light, sealed in dry place|
|Items of analysis||Specification||Results|
|Description||Off-white to pule yellow crystalline powder||Complies|
|Clarity of Solution||Clear and not more opalescet than reference suspension 2||Complies|
|Loss on drying||2.0~3.0%||2.5|
|Conclusion||Conforms with enterprise standards|