n acetyl l cystein , also known as N-acetylcysteine or Acetylcysteine (NAC), White crystalline powder with garlic-like odor and sour taste. Hygroscopic, easily soluble in water or ethanol, insoluble in ether and chloroform. It is acidic in aqueous solution (pH 2-2.75 in 10g / L H2O), mp101-107 ° C.
This product is an N-acetylated derivative of cysteine. The molecule contains a thiol group, which can break the disulfide bond (-SS-) of the mucin peptide bond, so that the mucin chain becomes a small molecule peptide chain, reducing Mucoid is viscous, so this product is a sticky sputum, purulent sputum, and a solution of respiratory mucus.
It is used as phlegm dissolving medicine. Applicable to respiratory obstruction caused by a large number of sticky sputum obstruction. It can also be used for detoxification of acetaminophen poisoning. Because this product has a special odor, it is easy to cause nausea and vomiting. It has a stimulating effect on the respiratory tract and can cause bronchospasm. It is generally used in combination with bronchodilators such as isoproterenol and sputum extraction with a suction device. Should not be in contact with metals (such as Fe, Cu), rubber, oxidants and so on. Should not be used in combination with antibiotics such as penicillin, cephalosporin, tetracycline, etc., so as not to reduce its antibacterial effect. Bronchial asthma should be used with caution.
||Protected from light
|Items of analysis
||White crystalsorcry stalline powder
|State of solution
|Other amino acids
||Chromato graphically not detectable ≤0.5%
|Loss on drying
||Conforms with enterprise standards