Pharmaceutical grade Allopurinol API blood pressure for tumor lysis cas 315-30-0

Basic Information
Place of Origin: China
Brand Name: Sigma
Certification: ISO
Model Number: Allopurinol
Minimum Order Quantity: 25kg
Price: USD68-85per kg
Packaging Details: 1kg/bag,25kg/drum
Delivery Time: 3 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 1000kg per month
Detail Information
Name: Allopurinol Cas No.: 315-30-0
EINECS NO.: 206-250-9 Purity: 99%min
MF: C5H4N4O Form: Powder
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Product Description

Pharmaceutical grade Allopurinol API blood pressure for tumor lysis cas 315-30-0
Allopurinol Introduction
Product Name Allopurinol
Chemical Name 4-hydroxypyrazolo[3,4-d] pyrimidine
CAS Number 315-30-0
Molecular Formula C5H4N4O
Molecular Weight 136.1
Allopurinol Function

Allopurinol used primarily in gout attack phase and the chronic phase, applied to generate too much uric acid, uricosuric allergy or is invalid, as well as urination drugs should not be used (such as renal insufficiency) of primary and secondary gout, hyperuricemia control. The drug can also be combined with uricosuric to enhance efficacy, especially in serious tophi and kidney patients is good.

1. Gout and hyperuricemia
Subsequently the uric acid lowering capacity of allopurinol was noted and the drug went on to be developed for its more famous use: to treat hyperuricemia (excess uric acid in blood plasma) and its complications. Allopurinol CAS 315-30-0does not alleviate acute attacks of gout, and there is currently controversy over the issue of whether it can actually make acute gout attacks worse initially, but is useful in chronic gout to prevent future attacks.
2. Tumor lysis syndrome
Allopurinol CAS 315-30-0 was also commonly used to treat tumor lysis syndrome in chemotherapeutic treatments as these regimes can rapidly produce severe acute hyperuricemia, although it has gradually been replaced by urate oxidase therapy.
Allopurinol Application
1.Allopurinol reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.
2. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.

Allopurinol Specification

PRODUCT NAME Allopurinol
CAS no. 315-30-0 Outer packing 1KG/foil bag
Storage Store in a well-closed container away from moisture
Items of analysis Specification Results
Description White or almost white powder White powder
Solubility Very slightly soluble in water and alcohol practically insoluble in dissolves in dilute solutions of the alkali hydroxide. Complies
Identification Infrared absorption(197K),The IR absorption spectrum of sample exhibits the same spectrum as Reference Standard Complies
Loss on drying ≤0.5% 0.12%
Related substances by HPLC Impurity A≤0.2% 0.03%
  Impurity B≤0.2% Not detected
  Impurity C≤0.2% Not detected
  Impurity D≤0.2% 0.03%
  Impurity E≤0.2% 0.02%
  Impurity F≤0.2% Not detected
  Any individual unspecified impurity≤0.1% 0.02%
  Total impurity≤1.0% 0.30%
Limit of hydrazine ≤10ppm Complies
Assay 98.0%~101.0% 99.96%
Conclusion Conforms to USP38 standard

Pharmaceutical grade Allopurinol API blood pressure for tumor lysis cas 315-30-0 0

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