products

Pharmaceutical DMSA powder API buy online for sale cas 304-55-2

Basic Information
Place of Origin: China
Brand Name: Sengmei
Certification: ISO
Model Number: DMSA
Minimum Order Quantity: 1kg
Price: USD600-900per kg
Packaging Details: 1kg/bag,25kg/drum
Delivery Time: 3 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 80kg per month
Detail Information
Name: DMSA Cas No.: 304-55-2
EINECS NO.: 206-155-2 Purity: 99%min
MF: C4H6O4S2 Form: Powder
High Light:

diclofenac potassium powder

,

pure paracetamol powder


Product Description

Pharmaceutical DMSA powder API buy online for sale cas 304-55-2

DMSA Introduction

DMSA Powder is the organosulfur compound with the formula HO2CCH(SH)CH(SH)CO2H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour. It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as achelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water soluble and non-toxic substance.

DMSA Function

DMSA Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood–brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.

DMSA Application

Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.

The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound DMSA.

DMSA Specification

Product Name: Succimer

CAS Number:304-55-2 Batch Size: 355kg

Item Standard Result
Identification Positive Positive
Characteristics White or off-white powder White powder
Odor &Taste Characteristic Characteristic
PH 2.5-3.0 2.7
Mesh size 60-100 Pass
Loss on drying 1.0% 0.07%
Heavy metal

As≤1.5ppm

Cd≤1ppm

Hg≤3ppm

Pb≤3ppm

Absent

Absent

Absent

Pass

microbiological test

Total bacterial Count

 

≤3,000/g

 

Pass
Total Mold&Yeast Count ≤300/g Pass
Salmonella

 

Absent

 

 

Absent

 

E.Coli

 

Absent

 

 

Absent

 

 

Staphylococcus Aureus

 

 

Absent

 

 

Absent

 

P.aeruginosa

 

Absent

 

 

Absent

 

Residual Solvent

Acetone≤5000ppm

Ethanol≤5000ppm

Ethyl acetate≤600ppm

Hexane≤290ppm

absent

80ppm

absent

absent

Residue on ignition 0.1% 0.04%
Assay 99.0%~101.0% 99.35%
Conclusion: Compiles With CP2015 standers.
 

Contact Details
susie

Phone Number : 8613228098753

WhatsApp : +8613228098753