N-acetyl-l-cysteine, also known as N-acetylcysteine or Acetylcysteine (NAC), is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Other uses include sulfate repletion in conditions, such as autism, where cysteine and related sulfur amino acids may be depleted.
N-acetyl-l-cysteine is a derivative of cysteine where an acetyl group is attached to the nitrogen atom. This compound is sold as a dietary supplement commonly claiming antioxidant and liver protecting effects. It is used as a cough medicine because it breaks disulfide bonds in mucus and liquefies it, making it easier to cough up. It is also this action of breaking disulfide bonds that makes it useful in thinning the abnormally thick mucus in cystic and pulmonary fibrosis patients.
1. N-acetyl-l-cysteine helps to prevent crusting in people with tracheostomy
2. Acetaminophen tylenol poisoning
3. N-acetyl l-cysteine can reduce mucus and help with breathing in various lung conditions
4. Cystic fibrosis
||Protected from light
|Items of analysis
||White crystalsorcry stalline powder
|State of solution
|Other amino acids
||Chromato graphically not detectable ≤0.5%
|Loss on drying
||Conforms with enterprise standards