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Monobenzone, also called 4-(Benzyloxy)phenol and monobenzyl ether of hydroquinone (MBEH) is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. It is a colourless solid that is classified as the monobenzyl ether of hydroquinone. Monobenzone is soluble in alcohol, benzene, and diethyl ether, and practically insoluble in water.
Monobenzone is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. It is a colourless solid that is classified as the monobenzyl ether of hydroquinone.
Monobenzone is used to treat the loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo.
Do not use this medication for other skin color conditions (e.g., freckling, age spots)
How To Use Monobenzone?
To get the best results apply a thin film of Monobenzone twice or thrice daily on the affected area. As the skin becomes very sensitive to sunlight with the use of the cream, it is important that you protect your skin from direct sunlight exposure. You should cover the skin properly and use a good sunscreen lotion before going out in order to protect your skin from sunlight. If possible, avoid outdoor activities during the medication. You can see remarkable results within three to four months. After Monobenzone cures your skin, you have to continue the application twice a week to maintain the skin color.
1. Monobenzone Powder is a compound used as a topical drug for medical depigmentation.
2. The topical application of monobenzone powder in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
3. Monobenzone Powder may cause destruction of melanocytes and permanent depigmentation.
4. The histology of the skin after depigmentation with topical monobenzone powder is the same as that seen in vitiligo.
5. The epidermis is normal except for the absence of identifiable melanocytes.
|Storage||In an airtight container, protected from light.|
|Items of analysis||Specification||Results|
|Appearance||White fine powder||Complies|
|Melting point||120-122 ℃||Complies|
|Loss on drying||≤0.5%||0.2%|
|Conclusion||Conforms with Specification|