Dark Red Raw Material Methylcobalamin B12 Powder With HPLC Test Method

Basic Information
Place of Origin: China
Brand Name: Sengmei
Certification: ISO
Model Number: methylcobalamin b12
Minimum Order Quantity: 10gram
Price: USD 5~10/gram
Packaging Details: 1kg/bag;25kg/Durm
Delivery Time: 1-3work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg per Month
Detail Information
Name: Methylcobalamin B12 CAS: 13422-55-4
EINECS: 236-535-3 Color: Dark Red
MOQ: 10gram Form: Powder
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Product Description

Pure raw material methylcobalamin b12 Mecobalamin CAS 13422-55-4

Methylcobalamin Vitamin B12 Description

Vitamin B12, vitamin B12 or vitamin B-12, also called cobalamin, is a water- soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production. Neither fungi, plants, nor animals are capable of producing vitamin B12. Only bacteria and archaea have the enzymes required for its synthesis, although many foods are a natural source of B12 because of bacterial symbiosis. The vitamin is the largest and most structurally complicated vitamin and can be produced industrially only through bacterial fermentation-synthesis.

Methylcobalamin Vitamin B12 Function

Mecobalamin is a vitamin B12 derivative. It is named after the chemical structure. It should be called “methyl vitamin B12”. Its methylated functional group can participate in the methyl transfer activity in the biochemical process of the body, and the nucleic acid and protein of the nerve tissue. It promotes the metabolism of fat, stimulates the synthesis of lecithin in Schwann cells, repairs the myelin sheath, and improves the nerve conduction velocity; it can directly enter nerve cells and stimulate the regeneration of axonal damaged areas; stimulate the protein synthesis of nerve cells, strengthen Axonal anabolism prevents axonal degeneration; participates in nucleic acid synthesis and promotes hematopoiesis. Clinically, it is often used for the treatment of diabetic neuropathy, and long-term use has a certain effect on the macrovascular complications of diabetes.
Mecobalamin is a therapeutic drug for peripheral neurological disorders. Compared with other vitamin B12 preparations, it has a good transferability to nerve tissue. It can promote nucleic acid-protein-lipid metabolism and repair damaged nerve tissue through methylation reaction. It plays a coenzyme role in the synthesis of methionine by homocysteine, especially in the synthesis of thymidine by deoxyuridine, which promotes the synthesis of DNA and RNA. In addition, in the experiment of glial cells, the drug increases the activity of methionine synthetase to promote the synthesis of myelin lipid lecithin. Improve the metabolic disorder of nerve tissue, promote the synthesis of axon and its protein, make the transport speed of skeletal protein close to normal, and maintain the function of axon. Mecobalamin injection also inhibits abnormal excitation conduction of nerve tissue, promotes maturation, division and improvement of anemia of positive red blood cells. Mecobalamin can quickly restore the number of red blood cells, hemoglobin, and hematocrit in rats reduced by B12 deficiency. It is applied to megaloblastic anemia and peripheral nerve disorders caused by vitamin B12 deficiency.
Methylcobalamin Vitamin B12 Specification
PRODUCT NAME Mecobalamin(Vitamin B12)
CAS no. 13422-55-4 Quantity 80kg
Storage Protected from light and seal
Items of analysis Specification Results
Characters Dark red crystal or crystalline powder Complies
Identification IR Complies
  HPLC Complies
  UV Complies
Related subtances Any impurity≤0.5% <0.06%
  Total impurity ≤2.0% <0.14%
Heavy Metals ≤20ppm <10ppm
Water ≤12.0% 3.62%
Assay 98.0%~102.0% 98.6%
Conclusion Conforms to enterprise standard


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