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CAS 58066-85-6 Pharmaceutical Raw Material Pure Miltefosine Powder Medicine Standard

Basic Information
Place of Origin: China
Brand Name: Miltefosine
Certification: ISO
Model Number: Miltefosine powder
Minimum Order Quantity: 10 grams
Price: Inquiry
Packaging Details: 10g/bag;25kg/Durm
Delivery Time: 1-3work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg per Month
Detail Information
Name: Miltefosine CAS: 58066-85-6
EINECS: 622-572-6 Standard: Medicine
Solubility: H2O: Soluble10mg/mL, Clear, Colorless Product Type: Powder
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Product Description

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Miltefosine Description
Miltefosine is an alkylphosphocholine drug with demonstrated activity against various parasite species and cancer cells as well as some pathogenic bacteria and fungi. For 10 years it has been licensed in India for the treatment of visceral leishmaniasis (VL), a fatal neglected parasitic disease. It is the first and still the only oral drug that can be used to treat VL and cutaneous leishmaniasis (CL).

Miltefosine Function

Miltefosine is a phospholipid drug. Chemically it is a derivative of alkylphosphocholine compounds discovered in the early 1980s. It was developed in the late 1980s as an anticancer drug. Simultaneously but independently it was found that the drug could kill Leishmania parasites, and since the mid-1990s successful clinical trials were conducted. The drug became the first (and still the only prescribed) oral drug in the treatment of leishmaniasis.

It is now known to be a broad-spectrum antimicrobial drug, active against pathogenic bacteria and fungi, as well as humantrematode Schistosoma mansoni.

Miltefosine is usedfor the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trialsfor this use in several other countries, such as Brazil and Guatemala. Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.

Miltefosine Specification

 

PRODUCT NAME Miltefosine
Batch number ACT20190926 Quanity 120kg
Cas number 58066-85-6    
Storage Sealed to keep away from moisture
Items of analysis Specification Results
Appearance Off-white to white powder white powder
Identification(byMS,IR,1H-NMR,13C-NMR,31P-NMR) Corresponds to structure Conforms
Water(K.F.) NMT5.0% 4.5%
PH of 1% solution in water Between 4.0~8.0 PH5.6

Clarity (1.0% in H2O;

1.0% in Methanol)

Clear and colorless solution Conforms

Related substance(TLC)

Choline chloride

Other Individual Impurity

Total Impurity

 

NMT 1.0%

NMT 1.0%

NMT 2.0%

 

Conforms

Conforms

Conforms

Assay(HCIO4) 98.0%~102.0%,Wite the anhydrous substance 99.8%

 

Conclusion

 

Conform with enterprise standard

 

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