|Place of Origin:||China|
|Model Number:||mast cell stabilizer sodium cromoglycate|
|Minimum Order Quantity:||1kg|
|Delivery Time:||3 work days|
|Payment Terms:||T/T, Western Union, MoneyGram|
|Supply Ability:||80kg per month|
|Name:||DMSAmast Cell Stabilizer Sodium Cromoglycate||Cas No.:||15826-37-6|
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Mast cell stabilizer sodium cromoglycate Introduction
Product name: Mast cell stabilizer sodium cromoglycate
Appearance : white powder
Molecular weight : 468.37
Molecular formula: C23H14Na2O11
Mast cell stabilizer sodium cromoglycate, also known as disodium cromoglycate, has a good preventive and therapeutic effect on allergic reactions. Its mechanism of action is to stabilize the cell membrane of mast cells, prevent mast cells from degranulation, thereby inhibiting the release of allergic reaction media such as histamine, serotonin and slow-reacting substances, thereby suppressing the adverse effects of allergic reaction medium on tissues. Its inhibition of the release of allergic mediators may be due to inhibition of intracellular cyclophosphophosphonate phosphodiesterase, resulting in an increase in the concentration of intracellular cyclophosphoside (cAMP), preventing the transport of calcium ions into mast cells, thereby stabilizing hypertrophy. The cell membrane prevents the release of allergic reaction media.
Mast cell stabilizer sodium cromoglycate Function
Stabilizes mast cells, which release histamine and other mediators of allergic reactions.
After oral inhalation, approximately 8% is absorbed from the lungs; up to 1% is absorbed from the GI tract after oral administration.
Management of bronchial asthma or prevention of acute bronchospasm (oral inhalation); prevention and relief of nasal symptoms of hay fever and other nasal allergies, including runny/itchy nose, sneezing, and allergic stuffy nose (intranasal); treatment of mastocytosis (oral solution); treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis (ophthalmic).as eye drops(Opticrom and Optrex Allergy (UK), Crolom) for allergic conjunctivitis.
Mast cell stabilizer sodium cromoglycate Specification
|Loss on Drying||≤0.5%||0.06%|
|Residue on Ignition||≤0.2%||Complies|
|Related substances||Any impurity NMT 0.1%||0.03%|
|Assay||98.0% to 99.0%||99.0%|